Pre-Implementation Genetic Diagnosis (PGD) - Why Acacio Fertility Center's decision is science-based

User Rating: / 7

Infertility topics explained by Brian Acacio, M.D..

"A research journal just published this month provides further evidence that the Array-CHG test chosen by Dr. Acacio is the only validated test for Preimplantation Genetic Diagnosis."

I recall being asked by several patients about Preimplantation Genetic Diagnosis (also known as "Preimplantation Genetic Screening (PGS)).   Acacio Fertility Center only uses Reprogenetics and their Array-CHG to help our patients.    This decision is supported by the latest research journal published by the American Society for Reproductive Medicine (Fertility and Sterility, Vol. 95, No. 3, March 1, 2011).

Genetic Diagnosis increases the precision of an infertility specialist's diagnostic capability.  Such precision is needed to guide treatment protocols.   I rely on accurate tools such as Reprogenetics' Array-CHG to customize treatment plans for each patient because time is of the essence, and tests with greater range of variability can result in mediocre treatment plans and ultimately unnecessary waste of energy and resources, not to mention prolonging the treatment.

There are many reasons for my choice of Reprogenetics.  Primarily, Reprogenetics is the only genetics laboratory that publishes a lot of research.   Diagnostic tests need to be validated with research.  That involves putting a group of patients through different experimental diagnostic tests and comparing the outcome of the tests to the "gold standard."  The diagnostic tests that have greater "power" to detect its intended target have greater reliability and predictive value.  On the other hand, those tests that have not gone through research validation are considered "non-validated."

The array CGH is now the ONLY preimplantation genetic diagnosis (PGD) test that is now "validated".   Acacio Fertility Center does not recommend other "non-validated" technologies.

CLICK HERE TO READ THE JOURNAL ARTICLE - "Validation of microarray comparative genomic hybridization for comprehensive chromosome analysis of embryos.  (Authored by Drs. Gutierrez-Mateo, Colls, Sanchez-Garcia et al).   Fertility and Sterility, Vol 95, No. 3, March 1, 2011.  pages 953-958."




Acacio Tweets

Dr. Acacio at PCOGS

Dr. Acacio presenting his research at PCOGS annual meeting. 10/2/2013 - 10/6/2013 in WA.

Pacific Coast OBGYN Society is the most prestigious medical conference on the West Coast.

Live Webinars

Join live Webinar Series: "Fertility 101: What to Expect at Your First Consultation"

Hosted by Dr. Acacio


Acacio on NBC

(New) Watch Dr. Acacio on a TV interview with NBC as he explains various aspects of infertility.


Top RE Doctor

Dr. Brian Acacio is recognized as among the top 10% Reproductive Endocrinologists in the country.

Becoming Pregnant...

Looking for tools to plan your conception, or having questions about how to increase your chance of becoming pregnant?  Visit “HELP FOR YOUR JOURNEY” section on the top navigation bar.

High Success Rates

Acacio Fertility Center's success rates are among the highest in the nation.